Institutional
Biological & Chemical Safety Committee (IBC)
Recombinant DNA and Hazardous Materials Protocol
Form FAQ
1. How much detail do you need
on this form?
The purpose of this form is to
provide enough information for the Institutional Biosafety Committee
to be able to evaluate the risk of
your experiments. Provide the basic framework of your experiments so
that we can understand how each of your reagents will be used. Even
if your protocol is essentially the same as another investigator’s,
please do not merely reference their name as we will not always have
that protocol at hand when reviewing yours.
2. I’m using dozens
of cell lines/genes. Do I need to list each one on the form?
No; you can group cell lines together in broad categories such as
murine immortal or human established. Genes can be listed as families,
so long as each member of the family has basically the same risk level.
If you are screening a library, provide the source of the library.
3. How long will it be until my protocol is approved?
That depends on the timing of your submission relative to the next
IBC meeting. We will make every effort to review your protocol prior
to the next meeting and ask you to provide any extra information we
feel the committee may need to make a decision. We appreciate your
cooperation and patience during this process.
4. How do I submit an amendment?
We recommend that you keep an electronic
version of your initial protocol and, when amendments are necessary,
make any changes on the electronic
version in a different color or font. You can then email, fax, or campus-mail
the new form to the EH&S office.
5. How much information do you need about my retroviral/lentiviral
vector system?
We need to know the source genome of the vector and how it has been
rendered replication-defective. We also need to know the packaging
cell line and the tropism of the resultant recombinant virus. If the
vector and/or cell line are commercially available, please provide
the company name and technical name of the vector/cell line.
